Our principal objective is to understand the molecular mechanism of epigenetic gene regulation and roles of epigenetics in health and disease. We also study how germ-lineage cell development in mammals is regulated. To address above questions, we transgenic and gene-targeting technology.
Laboratory of Mammalian Molecular Biology Keyword
mouse regulation of gene expression production of knock-out mouse epigenetics development chromatin post-translational modification development and differentiation of germ cell ES cell genome