Laboratory of Genetics

Professor

IGAKI, Tatsushi
igaki -at- lif.kyoto-u.ac.jp

Assistant Professor

ENOMOTO, Masato
menomoto -at- lif.kyoto-u.ac.jp

Program-Specific Assistant Professor

TANIGUCHI, Kiichiro
taniguchi.kiichiro.3c -at- kyoto-u.ac.jp

Main theme

Our research focuses on the molecular basis of cell-cell communication that governs tissue growth, homeostasis, and cancer. We take advantage of the powerful genetics of Drosophila.

Research Subjects

  1. Mechanism of cell competition
  2. Genetic basis of tissue growth regulation
  3. Molecular basis of tumor progression and metastasis
  4. Mechanism of aging

Left:Polarity-deficient cells (green; losers) are eliminated from epithelium by wild-type cells (magenta; winners) through cell competition. 
Right:Malignant tumor cells (magenta) are invading and metastasizing from the eye disc to the brain (blue) in Drosophila larva.

 

 

Web site 

 

Laboratory of Genetics Keyword

cell competition  cancer  cell-cell communication  tissue growth regulation  signal transduction  cellular senescence  fruit fly (Drosophila)  genetics  development  pattern formation  developmental robustness  apoptosis