igaki -at- lif.kyoto-u.ac.jp
menomoto -at- lif.kyoto-u.ac.jp
Program-Specific Assistant Professor
taniguchi.kiichiro.3c -at- kyoto-u.ac.jp
Our research focuses on the molecular basis of cell-cell communication that governs tissue growth, homeostasis, and cancer. We take advantage of the powerful genetics of Drosophila.
- Mechanism of cell competition
- Genetic basis of tissue growth regulation
- Molecular basis of tumor progression and metastasis
- Mechanism of aging
Left：Polarity-deficient cells (green; losers) are eliminated from epithelium by wild-type cells (magenta; winners) through cell competition.
Right：Malignant tumor cells (magenta) are invading and metastasizing from the eye disc to the brain (blue) in Drosophila larva.
Laboratory of Genetics Keyword
cell competition cancer cell-cell communication tissue growth regulation signal transduction cellular senescence fruit fly (Drosophila) genetics development pattern formation developmental robustness apoptosis