Department of Signal Transductions


Laboratory of Molecular Neurobiology

■Professor

NEGISHI, Manabu
mnegishi -at- pharm.kyoto-u.ac.jp

■Associate Professor

KATOH, Hironori
hirokato -at- pharm.kyoto-u.ac.jp

■Assistant Professor

OINUMA, Izumi
izu-oinuma -at- lif.kyoto-u.ac.jp

■Main theme

Laboratory of Molecular NeurobiologyOutline of Teaching Activities
The laboratory provides seminars which review and discuss recent progress in molecular mechanisms of neuronal functions

Outline of Research Activities
The main themes of research in this laboratory are the molecular mechanisms underlying neuronal network formation and neuronal signal transductions.

  1. Neuronal functions and signal transductions of GTP-binding proteins
  2. Molecular mechanisms for axon guidance
  3. Regulatory systems of synaptic transmission
  4. Signal transduction of neuronal polarity formation

Web site

Laboratory of Genetics

■Professor

IGAKI, Tatsushi
igaki -at- lif.kyoto-u.ac.jp

■Assistant Professor

NAITO, Yuko
yuko -at- lif.kyoto-u.ac.jp

■Main theme

Our research focuses on the molecular basis of cell-cell communication that governs tissue growth, homeostasis, and cancer. We take advantage of the powerful genetics of Drosophila.

  1. Mechanism of cell competition
  2. Genetic basis of tissue growth regulation
  3. Molecular basis of tumor progression and metastasis

Laboratory of Genetics 
Left:Polarity-deficient cells (green; losers) are eliminated from epithelium by wild-type cells (magenta; winners) through cell competition.
Right:Malignant tumor cells (magenta) are invading and metastasizing from the eye disc to the brain (blue) in Drosophila larva.