Department of Signal Transductions
Laboratory of Molecular Neurobiology
mnegishi -at- pharm.kyoto-u.ac.jp
hirokato -at- pharm.kyoto-u.ac.jp
izu-oinuma -at- lif.kyoto-u.ac.jp
Outline of Teaching Activities
The laboratory provides seminars which review and discuss recent progress in molecular mechanisms of neuronal functions
Outline of Research Activities
The main themes of research in this laboratory are the molecular mechanisms underlying neuronal network formation and neuronal signal transductions.
- Neuronal functions and signal transductions of GTP-binding proteins
- Molecular mechanisms for axon guidance
- Regulatory systems of synaptic transmission
- Signal transduction of neuronal polarity formation
Laboratory of Genetics
igaki -at- lif.kyoto-u.ac.jp
yuko -at- lif.kyoto-u.ac.jp
Our research focuses on the molecular basis of cell-cell communication that governs tissue growth, homeostasis, and cancer. We take advantage of the powerful genetics of Drosophila.
- Mechanism of cell competition
- Genetic basis of tissue growth regulation
- Molecular basis of tumor progression and metastasis
Left：Polarity-deficient cells (green; losers) are eliminated from epithelium by wild-type cells (magenta; winners) through cell competition.
Right：Malignant tumor cells (magenta) are invading and metastasizing from the eye disc to the brain (blue) in Drosophila larva.