ksakamak -at- lif.kyoto-u.ac.jp
Apoptosis, or programmed cell death, plays an important role in many biological processes, including embryogenesis, maintenance of tissue homeostasis, and elimination of improper cells such as unfunctional or harmful cells in both animals and plants. Our main research project is to understand the molecular and cellular mechanisms of apoptotic cell death in vitro and in vivo, using cultured cells, medaka and mouse as model systems. We also investigate to develop new methods and techniques for imaging and simulating of such a vital phenomenon. In conjunction with these studies, we have been challenging to pursue the biological significance of cell death.
Laboratory of Molecular and Cellular Biology Keyword
apoptosis bioimaging biosensor caspase cancer cell death developmental biotechnology molecular evolution model animals optogenetics signal transduction simulation