Laboratory of Developmental Dynamics


KAGEYAMA, Ryoichiro
rkageyam -at-

Associate Professor

OHTSUKA, Toshiyuki
tohtsuka -at-

Assistant Professor

tkobayas -at-

Main theme

We analyze the molecular mechanism of embryonic development by using the most advanced methods such as imaging, optogenetics and transgenic mouse technologies. We evaluate mathematical modeling by using transgenic mice and seek to understand the principles of developmental dynamics. We found that oscillatory gene expression is important for many developmental processes such as brain morphogenesis and somite formation.



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Laboratory of Developmental Dynamics Keyword

cell differentiation  stem cell  oscillation of gene expression  biological clock   segmentation clock  mathematical model  transcription factor  optogenetics  transgenic mice