Laboratory of Signal Transduction

Lecturer

KUSAKABE, Morioh
morioh -at- lif.kyoto-u.ac.jp

Assistant Professor

MIYATA, Yoshihiko
ymiyata -at- lif.kyoto-u.ac.jp

Main theme

We are interested in identifying and elucidating molecular mechanisms that regulate cell proliferation, cell differentiation, cell cycle, aging and developmental processes. The current topics include 1) regulatory mechanisms and functions of the MAP kinase cascade pathways, 2) identification of novel signal transduction mechanisms, 3) molecular mechanisms for life span regulation, 4) roles of protein kinases in cell cycle progression and regulation, 5) growth factor signaling mechanisms in developmental processes, 6) regulatory mechanisms for mammalian circadian clock.

Web Site

 

Microinjection into Xenopus laevis embryos at the cleavage stage

Multiciliated cell differentiation in a salt-and-pepper pattern

 

Laboratory of Signal Transduction Keyword

signal transduction  regulation of life span and aging  development and differentiation  cell fate determination  iPS  MAP kinase  bioinformatics  biological clock (or circadian clock)  transcriptional regulation  regulation of cell proliferation