Division of Integrated Life Science

Laboratory of Aging and Infection Control

Research summary

Research outline

Using C. elegans and mice as model organisms, we are studying the mechanisms of aging and infection and how to control them. For example, we have shown that certain intestinal bacteria delay the expression of aging markers and extend healthy life span. Bacteria are a truly diverse population of strains, from pathogenic to beneficial, even within the same species, and we aim to clarify these differences to gain a comprehensive understanding of their interactions with the host. We are also developing methods to extend healthy life span, focusing on mechanisms such as mitochondrial quality control and epigenetics, which are closely related to aging. We invite you to join us in our research.

Main themes

  • Methods to control aging and elucidation of its mechanisms
  • Imaging technology focusing on mitochondria and epigenetics
  • Anti-infective effects and improvement of host resistance against bacterial infection
  • Host inflammation suppression by intestinal bacteria
  • Interaction between host and skin and gut microbiota


KAGE-NAKADAI, ErikoProfessor

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