Coming Soon

1. Elucidating physiological roles of PIEZO expressing mechanosensory neurons innervating lung and/or other organs. We have been specifically investigating their contribution to breathing pattern of newborns, as starting breathing immediately after birth is critical for survival of mammalian newborns and its underlying mechanism is still mostly elusive.
2. Studying the contribution of PIEZO mediated mechanosensation in the brain, focusing on both developmental process and brain function.
3. Studying the mechanism in which PIEZO1 mediated mechanosensation contributes to venous/lymphatic valve formation, utilizing KO or reporter mouse lines and cultured endothelial cells.