Division of Integrated Life Science

Laboratory of Cell Recognition and Pattern Formation

Research summary

Research outline

We are trying to unravel underlying mechanisms of adaptations to nutrient balances using Drosophila species. We are also taking interspecies approaches to understand contributions of symbiotic microorganisms to animal growth and reproductive manipulation (“male killing”). By using Drosophila somatosensory neurons, we are dissecting operating principles of neuronal circuits that evoke selective behavioral outputs in response to thermal or mechanical nociceptive stimuli. We are also interested in how genomic information and cells cooperatively build up the entire body of an organism, and trying to understand common principles of epithelial morphogenesis beyond hierarchies of genome, cells and tissues. To conduct these studies, we make full use of molecular, optogenetic, and physiological approaches, imaging, single-cell analysis and multi-omics.

Main themes

  • Nutri-developmental biology: deciphering regulatory systems of host animals and symbiotic microorganisms that govern nutritional adaptability to ensure animal growth, reproduction, and aging
  • Neuroscience: operating principles of neuronal circuits that evoke selective behavioral outputs in response to nociceptive stimuli
  • Morphogenesis: common principles of epithelial morphogenesis beyond hierarchies of genome, cells and tissues
  • Reproductive parasites: a comprehensive study of “male killing” caused by insect symbionts

Member

UEMURA, TadashiProfessor

uemura.tadashi.5m*kyoto-u.ac.jp See faculty
information

USUI, TadaoSenior Lecturer

usui.tadao.3c*kyoto-u.ac.jp See faculty
information

HATTORI, YukakoAssistant Professor

hattori.yukako.3e*kyoto-u.ac.jp See faculty
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HARUMOTO, ToshiyukiProgram-Specific Assistant Professor

harumoto.toshiyuki.5c*kyoto-u.ac.jp See faculty
information
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Movie of research introduction

Access

Faculty of Medicine Campus, Faculty of Medicine Bldg. G South Campus Research Bldg.

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