Laboratory of Bioimaging and Cell Signaling


MATSUDA, Michiyuki
matsudam -at-

Associate Professor

TERAI, Kenta
terai.kenta.5m -at-

Assistant Professor

SATO, Shinya
sato.shinya.7e -at-

Main theme

We are visualizing the growth signal transduction cascades in living cells by using biosensors based on the principle of Foerster resonance energy transfer (FRET). These FRET videos are used to characterize the property of each signaling molecule. We are also developing transgenic mice expressing FRET biosensors to observe the signaling status in living mice with two-photon excitation microscopes. We also study development and plasticity of nervous system by using in vivo imaging of mouse brain.

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Laboratory of Bioimaging and Cell Signaling Keyword

cancer  intracellular signal transduction  bioimaging  fluorescent biosensor  systems biology  quantitative analysis  intercellular signal transduction  inflammation  drug discovery  pathology