Laboratory of Genetics

Professor

IGAKI, Tatsushi
igaki -at- lif.kyoto-u.ac.jp

Assistant Professor

ENOMOTO, Masato
menomoto -at- lif.kyoto-u.ac.jp

Program-Specific Assistant Professor

TANIGUCHI, Kiichiro
taniguchi.kiichiro.3c -at- kyoto-u.ac.jp

Main theme

Our research focuses on the molecular basis of cell-cell communication that governs tissue growth, homeostasis, and cancer. We take advantage of the powerful genetics of Drosophila.

Research Subjects

  1. Mechanism of cell competition
  2. Genetic basis of tissue growth regulation
  3. Molecular basis of tumor progression and metastasis
  4. Mechanism of aging

Left：Polarity-deficient cells (green; losers) are eliminated from epithelium by wild-type cells (magenta; winners) through cell competition. 
Right：Malignant tumor cells (magenta) are invading and metastasizing from the eye disc to the brain (blue) in Drosophila larva.

 

 

Web site 

 

Laboratory of Genetics Keyword

cell competition　　cancer　　cell-cell communication　　tissue growth regulation　　signal transduction　　cellular senescence　　fruit fly (Drosophila)　　genetics　　development　　pattern formation　　developmental robustness　　apoptosis