Laboratory of Spatiotemporal Optical Control

Program-Specific Professor

ISOBE, Keisuke

Main theme

Two-photon fluorescence microscopy has become a powerful tool for deep imaging of biological tissues. However, many biological phenomena in which intercellular interaction and communication networks play a crucial role are invisible because of insufficient imaging performance of commercial two-photon fluorescence microscopes. We aim to make the invisible visible by creating novel optical techniques. Our current research focuses on the following subjects;

  1. Development of femtosecond lasers for ultra-deep imaging and their applications
  2. Development of wide-field deep imaging techniques using spatiotemporal control of laser pulses and their applications
  3. Development of 4-dimensional optical control techniques using multiphoton patterned illumination their applications